openEBGM: An R Implementation of the Gamma-Poisson Shrinker Data Mining Model

Abstract:

We introduce the R package openEBGM, an implementation of the Gamma-Poisson Shrinker (GPS) model for identifying unexpected counts in large contingency tables using an empirical Bayes approach. The Empirical Bayes Geometric Mean (EBGM) and quantile scores are obtained from the GPS model estimates. openEBGM provides for the evaluation of counts using a number of different methods, including the model-based disproportionality scores, the relative reporting ratio (RR), and the proportional reporting ratio (PRR). Data squashing for computational efficiency and stratification for confounding variable adjustment are included. Application to adverse event detection is discussed.

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Authors

Affiliations

Travis Canida

 

John Ihrie

 

Published

Nov. 21, 2017

Received

Aug 11, 2017

DOI

10.32614/RJ-2017-063

Volume

Pages

9/2

499 - 519

Supplementary materials

Supplementary materials are available in addition to this article. It can be downloaded at RJ-2017-063.zip

CRAN packages used

openEBGM, PhViD, mederrRank, tidyr, ggplot2, data.table

CRAN Task Views implied by cited packages

Bayesian, Finance, Graphics, HighPerformanceComputing, Phylogenetics

Footnotes

    Reuse

    Text and figures are licensed under Creative Commons Attribution CC BY 4.0. The figures that have been reused from other sources don't fall under this license and can be recognized by a note in their caption: "Figure from ...".

    Citation

    For attribution, please cite this work as

    Canida & Ihrie, "The R Journal: openEBGM: An R Implementation of the Gamma-Poisson Shrinker Data Mining Model", The R Journal, 2017

    BibTeX citation

    @article{RJ-2017-063,
      author = {Canida, Travis and Ihrie, John},
      title = {The R Journal: openEBGM: An R Implementation of the Gamma-Poisson Shrinker Data Mining Model},
      journal = {The R Journal},
      year = {2017},
      note = {https://doi.org/10.32614/RJ-2017-063},
      doi = {10.32614/RJ-2017-063},
      volume = {9},
      issue = {2},
      issn = {2073-4859},
      pages = {499-519}
    }