Profile Likelihood Estimation of the Correlation Coefficient in the Presence of Left, Right or Interval Censoring and Missing Data

Abstract:

We discuss implementation of a profile likelihood method for estimating a Pearson correla tion coefficient from bivariate data with censoring and/or missing values. The method is implemented in an R package clikcorr which calculates maximum likelihood estimates of the correlation coefficient when the data are modeled with either a Gaussian or a Student t-distribution, in the presence of left, right, or interval censored and/or missing data. The R package includes functions for conducting inference and also provides graphical functions for visualizing the censored data scatter plot and profile log likelihood function. The performance of clikcorr in a variety of circumstances is evaluated through extensive simulation studies. We illustrate the package using two dioxin exposure datasets.

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Published

Aug. 16, 2018

Received

Oct 1, 2017

DOI

10.32614/RJ-2018-040

Volume

Pages

10/2

159 - 179

Supplementary materials

Supplementary materials are available in addition to this article. It can be downloaded at RJ-2018-040.zip

CRAN packages used

clikcorr, survival, mvtnorm

CRAN Task Views implied by cited packages

ClinicalTrials, Distributions, Econometrics, Finance, Multivariate, SocialSciences, Survival

Footnotes

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    Citation

    For attribution, please cite this work as

    Li, et al., "The R Journal: Profile Likelihood Estimation of the Correlation Coefficient in the Presence of Left, Right or Interval Censoring and Missing Data", The R Journal, 2018

    BibTeX citation

    @article{RJ-2018-040,
      author = {Li, Yanming and Gillespie, Brenda W. and Shedden, Kerby and Gillespie, John A.},
      title = {The R Journal: Profile Likelihood Estimation of the Correlation Coefficient in the Presence of Left, Right or Interval Censoring and Missing Data},
      journal = {The R Journal},
      year = {2018},
      note = {https://doi.org/10.32614/RJ-2018-040},
      doi = {10.32614/RJ-2018-040},
      volume = {10},
      issue = {2},
      issn = {2073-4859},
      pages = {159-179}
    }